Posted from: Monday, October 05, 2015 - 04:46 PM - Present

Varubi Approved as an Antiemetic

September 1, 2015 – The U.S. Food and Drug Administration (FDA) granted Tesaro, Inc. approval for Varubi (rolapitant) as an antiemetic in the control of nausea and vomiting (emesis) by blocking receptors for substance P/neurokinin 1 (NK-1). Varubi is indicated to prevent delayed nausea and vomiting for adults undergoing emetogenic (vomit-causing) chemotherapy. About half of patients receiving some type of chemotherapy experience chemotherapy-induced nausea and vomiting (CINV) between 25 hours and 120 hours after getting the chemo. Varubi will be used along with a corticosteroid, dexamethasone, and a 5-HT3 blocker, such as granisetron or ondansetron to prevent such delayed CINV. Recommended dosing for Varubi is 180mg (two 90mg tablets) to be taken two hours or less before each cycle of chemotherapy begins. 

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Last Updated Friday, October 20, 2017 - 06:44 AM.