Posted from: Friday, October 30, 2015 - 12:06 PM - Present

Expanded Indication for Opdivo

October 9, 2015 - The U.S. Food and Drug Administration approved an expanded indication for Opdivo (nivolumab – Bristol Myers Squibb). Opdivo is an infused human programmed death receptor -1 (PD-1) inhibitor and the new indication allows Opdivo to be used to treat patients with metastic non-squamous non-small cell lung cancer (NSCLC) that progresses during or after treatment with platinum-based chemotherapy.

Opdivo was originally approved in December 2014 for the treatment of previously-treated patients with unresectable or metastatic melanoma. Then in March, 2015, the FDA approved Opdivo to treat patients with metastatic squamous NSCLC that progresses during or after treatment with platinum-based chemotherapy. Approximately 90% of patients with lung cancer have NSCLC, of which about 70% of the cases are non-squamous.

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Last Updated Friday, October 18, 2019 - 01:51 PM.