Posted from: Tuesday, April 04, 2017 - 03:29 PM - Present

Noctiva Approved to Treat Nighttime Urination

March 3, 2017 – The U.S. FDA approved Noctiva™ (desmopressin) nasal spray, manufactured by Serenity Pharmaceuticals. Noctiva is indicated to treat adults who have nocturnal polyuria. Also called nocturia, the condition wakes patients with the need to urinate twice or more during the night. An analog of the hormone vasopressin, Noctiva temporarily increases the amounts of water the kidneys reabsorb to decrease urine output during the night. Recommended dosing is one spray per day around a half an hour before bedtime. It will be dispensed in containers holding a 30-day supply of either 0.83mcg or 1.66mcg strength. A boxed warning on its labeling and a Medication Guide for patients caution that it may cause hyponatremia (abnormally low levels of blood sodium). Before it is prescribed, the patient should have a 24-hour urine collection test to measure nighttime urine production. Patients using it will need to have sodium levels checked before starting Noctiva, within one week, after one month and then at regular intervals. Several other brand and generic desmopressin products, including oral, injectable and nasal forms, are available in the United States, however, only Noctiva currently is approved for treating patients with nocturia. 

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Actual drug patent expiration dates and availability of new medications are subject to change due to patent litigation, settlement agreements, additional patents, exclusivities, and final FDA approval.  Distribution and availability of new medications at pharmacies may not occur immediately following FDA approval.  Patients are advised to speak with their healthcare professional or pharmacist regarding appropriateness as well as actual availability.

*This is provided for information only.  The reference to any medication above does not mean the medication is covered by your plan.

 

Last Updated Sunday, April 23, 2017 - 01:53 PM.