Generic Launched for Ziagen
August 17, 2017 – Camber Pharmaceuticals has launched its generic to ViiV Healthcare’s Ziagen® (abacavir) oral solution, indicated to treat HIV when used in combination with other antiretroviral drugs. A nucleoside reverse transcriptase inhibitor (NRTI), abacavir oral solution is approved for use in children three months of age and up, as well as for older patients who may have difficulty swallowing medication in tablet form. Recommended dosing for pediatric patients is based on weight. For adults, the recommended dosing is 600mg per day, either taken as a single dose or split into two doses. For patients who have been diagnosed with hepatic impairment, recommended dosing is 200mg twice daily. All abacavir products carry a black box warning cautioning patients of the risk of severe and potentially fatal hypersensitivity reactions, lactic acidosis, and hepatomegaly with steatosis.
Brand name Ziagen oral solution sales for 2016 were estimated at $2 million. Camber’s generic received its U.S. FDA approval in September of 2016, and is available in a 20mg/mL bottle containing 240 mL of oral solution.
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