Posted from: Tuesday, January 16, 2018 - 12:47 PM - Present

Rhopressa Approved to Lower Intraocular Pressure

December 18, 2017 – The U.S. FDA has approved Rhopressa® (netarsudil 0.02%) ophthalmic solution, manufactured by Aerie Pharmaceuticals, to reduce intraocular pressure in patients who have open-angle glaucoma or ocular hypertension. Rhopressa is the first drug in a new class known as rho kinase inhibitors.

Caused by excessive accumulation of aqueous humor (a fluid found inside of the eye), elevated intraocular pressure can lead to lasting damage that may result in vision loss. Rhopressa is thought to work by increasing the amount of aqueous humor that exits the eye through the trabecular meshwork. The trabecular meshwork, an area of tissue found at the base of the cornea, plays a key role in maintaining proper intraocular pressure. Rhopressa may also help to reduce the amount of fluid produced in the eye, and prevent the buildup of fibers in the trabecular meshwork.

Recommended dosing is one drop per day, in the evening, in the affected eye. Patients should take Rhopressa no less than five minutes before or after other topical ophthalmic medications they may be using. Missed doses should be delayed until the next evening, as Rhopressa is not well-tolerated if taken more than once per day. The product will be available in bottles containing 2.5mL of solution.

Rhopressa is the first product made by Aerie to receive FDA approval. A second product, Roclatan™ (netarsudil 0.02%/latanoprost 0.005%) ophthalmic solution, is currently in development. Aerie plans to launch Rhopressa during the second quarter of 2018. Pricing has not yet been announced.

Adverse reactions or quality problems experienced with the use of a recalled product may be reported to the FDA’s MedWatch Adverse Event Reporting Program either online, by U.S. mail or by fax.

Actual drug patent expiration dates and availability of new medications are subject to change due to patent litigation, settlement agreements, additional patents, exclusivities, and final FDA approval.  Distribution and availability of new medications at pharmacies may not occur immediately following FDA approval.  Patients are advised to speak with their healthcare professional or pharmacist regarding appropriateness as well as actual availability.

*This is provided for information only.  The reference to any medication above does not mean the medication is covered by your plan.

Last Updated Friday, May 18, 2018 - 11:23 PM.