Posted from: Tuesday, April 03, 2018 - 04:16 PM - Present

Ilumya Approved to Treat Plaque Psoriasis

March 21, 2018 – The U.S. FDA has approved Ilumya™ (tildrakizumab-asmn), manufactured by Sun Pharma, for the treatment of moderate-to-severe plaque psoriasis in adult patients who are candidates for systemic therapy or phototherapy.

An estimated six million individuals in the United States live with plaque psoriasis, a chronic immune disorder in which overproduction of skin cells leads to raised, red patches of skin on various parts of the body. The patches can become painful and subject to cracking and bleeding.

The latest in a new class of drugs known as interleukin-23 (IL-23) inhibitors, Ilumya works by selectively blocking a cytokine involved in the immune system’s inflammatory response. Recommended dosing is 100mg in Week 0, Week 4, and then every 12 weeks following. Ilumya will be available in single-use, prefilled syringes for subcutaneous injection.

Janssen’s Tremfya® (guselkumab), approved in July of 2017, was the first IL-23 inhibitor to reach the U.S. market. An additional IL-23 inhibitor, risankizumab, is currently in development with Boehringer Ingelheim and AbbVie, and may be approved in 2019.

Sun Pharma has not yet released pricing information for Ilumya. The product is expected to launch in June or July of 2018.

 

Adverse reactions or quality problems experienced with the use of a recalled product may be reported to the FDA’s MedWatch Adverse Event Reporting Program either online, by U.S. mail or by fax.

Actual drug patent expiration dates and availability of new medications are subject to change due to patent litigation, settlement agreements, additional patents, exclusivities, and final FDA approval.  Distribution and availability of new medications at pharmacies may not occur immediately following FDA approval.  Patients are advised to speak with their healthcare professional or pharmacist regarding appropriateness as well as actual availability.

*This is provided for information only.  The reference to any medication above does not mean the medication is covered by your plan.

 

Last Updated Saturday, December 15, 2018 - 10:04 PM.