Lyrica Receives Expanded Indication
May 3, 2018 – The U.S. FDA has approved an expanded indication for Lyrica® (pregabalin), manufactured by Pfizer, to be used as an adjunctive treatment for patients four years of age and older who have partial onset seizures.
In a clinical study, patients age four to 17 years who were treated with Lyrica at a dose of either 10mg/kg or 2.5mg/kg daily experienced a reduction in partial onset seizures compared to those who received a placebo. The higher dose of 10mg/kg demonstrated a greater reduction in partial onset seizures, and a higher rate of response. Recommended dosing under the new indication is based on weight and divided across two to three doses daily.
Lyrica was first approved in 2004, and is also indicated for the treatment of fibromyalgia, post herpetic neuralgia (PHN), neuropathic pain associated with diabetic peripheral neuropathy (DPN), and as an adjunctive therapy for adult patients with partial onset seizures, and fibromyalgia.
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