FDA Approves Xolremdi (mavorixafor) for Use in Patients with WHIM Syndrome
The FDA has approved Xolremdi™ capsules, manufactured by X4 Pharmaceuticals, for use in patients 12 years of age and older with WHIM syndrome (warts, hypogammaglobulinemia, infections and myelokathexis) to increase the number of circulating mature neutrophils and lymphocytes.
- WHIM syndrome is a rare, combined primary immunodeficiency and chronic neutropenic disorder caused by CXCR4 receptor dysfunction that results in impaired mobilization of white blood cells from the bone marrow into peripheral circulation. It is estimated that at least 1,000 people are currently diagnosed with WHIM syndrome in the U.S.
Source: X4 Pharmaceuticals
