Aspruzyo Sprinkle Approved for Chest Pain

March 3, 2022

The U.S. FDA has approved Aspruzyo Sprinkle™ (ranolazine – Sun Pharmaceuticals) to treat chronic angina (chest pain). The drug may be used in conjunction with beta-blockers, nitrates, calcium channel blockers, antiplatelet therapy, lipid-lowering therapy, angiotensin-converting enzyme inhibitors, and angiotensin receptor blockers.

  • Recommended dosing is 500mg taken twice daily. Dosing can be increased to a maximum of 1,000mg twice daily if needed based on clinical symptoms.
  • Aspruzyo Sprinkle is supplied in unit-dose sachets of 500mg or 1,000mg. Each sachet contains granules that are added on top of a tablespoon of soft food (such as applesauce or yogurt) for oral administration or given with water via nasogastric tube or gastric tube.
  • Launch and pricing information are not available.
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